Bone Marrow Biopsy: Can You Be Sedated? (2024)

Bone Marrow Biopsy: Can You Be Sedated? (1)Share on Pinterest

Bone marrow biopsies are performed to check for cancer and other diseases that impact your blood. A bone marrow biopsy is performed by inserting a large needle into your bone, usually your hip bone, to extract a bone marrow sample.

While this procedure can be intimidating, there are pain management options and techniques the doctor uses to help reduce or eliminate pain.

Receiving IV sedation is one option to reduce the pain and anxiety of a bone marrow biopsy. The sedation is used in combination with a local anesthetic and can make the procedure much easier for patients.

Bone marrow biopsies may also be done under general anesthesia, while you’re unconscious. But this is usually done if the procedure is performed during surgery or another procedure.

A bone marrow biopsy is a medical test that allows your bone marrow to be examined in a lab. Bone marrow is the soft tissue in the center of your bones that makes blood cells. Your bone marrow might need to be examined if you’re having trouble making blood cells.

The test can check for cancer of the blood like leukemia or lymphoma or to check if another type of cancer has spread to your bone marrow. If you’re already being treated for cancer, a bone marrow biopsy can check how your body is responding to chemotherapy.

Beyond cancer, a bone marrow biopsy can be used if you have:

  • unexplained anemia
  • low iron levels
  • abnormal numbers of any type of blood cell

A biopsy is done by inserting a small needle into your bone. A sample of your bone marrow is then extracted. The sample is sent to a lab and examined.

Read this for more information about a bone marrow biopsy.

You’ll always receive a local anesthetic before a bone marrow biopsy. Local anesthesia is given by injection at the site the biopsy will be performed. The local anesthesia will numb the site and reduce the pain of the bone marrow biopsy.

You can also choose to receive sedation during the procedure. Sedation can help manage any stress or fear you have about the bone marrow biopsy. It can also provide additional pain relief.

Sedation is offered in addition to the local anesthesia and is given via IV. You’ll receive it during the entire procedure. You’ll be awake under this type of sedation, but you’ll be relaxed and shouldn’t feel pain.

Your sedative might be a combination of a benzodiazepine, an anti-anxiety medication, and a pain medication. It could also be a benzodiazepine alone.

Research shows that using local anesthesia and sedation together is beneficial for patients having a bone marrow biopsy. Studies have found that there are several benefits to using sedation and local anesthetic including decreased anxiety and pain.

Some people might experience short-term amnesia under sedation. This means they may not form a memory of the biopsy and may have less distress. These benefits can make a bone marrow biopsy a lot easier.

Studies have shown that using sedation increases patient cooperation with the procedure and reduces patient fear about future bone marrow biopsy. Additionally, children report less pain and less distress when they receive sedation during a bone marrow biopsy.

There are some possible side effects associated with any type of IV sedation. But any side effects can be managed by the medical team performing the biopsy.

Side effects also resolve quickly once the biopsy is complete. For instance, you’ll receive oxygen during the procedure if the sedation is slowing down your breathing.

Additional possible side effects include:

  • nausea
  • headache
  • drowsiness

You’ll need to lie still during a bone marrow biopsy.

You’ll feel the biopsy site is cleaned with a sterile solution. You’ll be given local anesthesia once the sight is prepared. You’ll feel a small pinch when the local anesthesia is injected. The biopsy is then performed by inserting a large needle into the bone.

The doctor performing the procedure will rotate the needle inside your bone to collect the bone marrow sample. You might feel pain and pressure in your bone while the needle is inserted. The pain will stop when the needle is pulled back out.

A combination of local anesthesia and sedation can prevent you from feeling the pain and pressure. It can also help you lie still and relax during your biopsy.

Not everyone needs or wants sedation during their bone marrow biopsy. But for many people, sedation can help make the procedure much easier. It’s a good choice if you’re nervous about your bone marrow biopsy, especially since the side effects are minimal.

A local anesthetic is always given during a bone marrow biopsy. It’ll numb the area and reduce pain.

Receiving sedation in addition to a local anesthetic can provide additional pain relief and can reduce the distress of a bone marrow biopsy. Studies have shown that patients who receive sedation experience less pain and less anxiety.

Sedation is safe, with very few side effects.

Bone Marrow Biopsy: Can You Be Sedated? (2024)

FAQs

Bone Marrow Biopsy: Can You Be Sedated? ›

You'll be awake during the procedure, but your provider will numb the biopsy site (local anesthesia) to keep you comfortable. Before the procedure, you'll change into a hospital gown. Your provider may give you a sedative to help you relax.

How can I make my bone marrow biopsy less painful? ›

When a BMBA is performed in adults, a local anesthetic (LA), usually lidocaine or a similar drug, is used to numb the area of the skin and periosteum at the puncture site before the procedure. Lidocaine can be given along with sodium bicarbonate to reduce the burning pain of the lidocaine solution [35].

Why is a bone marrow biopsy so painful? ›

The biopsy needle may also cause a brief, usually dull, pain. Since the inside of the bone cannot be numbed, this test may cause some discomfort. If a bone marrow aspiration is also done, you may feel a brief, sharp pain as the bone marrow liquid is removed.

Can you be sedated for a biopsy? ›

Some biopsies can be done in a healthcare provider's office, while others need to be done in a hospital setting. In addition, some biopsies can be done with a local anesthetic to numb just the local area involved. Others may need sedation or even full anesthesia that puts you completely asleep during the procedure.

Is a bone marrow biopsy done in an operating room? ›

A biopsy is the removal of a small piece of marrow tissue by a special biopsy needle. Most of the time, this procedure is done under general anesthesia either in the clinic or in the operating room.

Can you request sedation for a bone marrow biopsy? ›

A bone marrow examination can be done with only local anesthesia to numb the area where the needles will be inserted. With local anesthesia, bone marrow aspiration, in particular, can cause brief, but sharp, pain. Many people choose to also have light sedation for additional pain relief.

Are you put to sleep for a bone biopsy? ›

If general anesthesia is used, you will be put to sleep using intravenous medicine. If local anesthesia is used to numb the area, you will need to lie still during the procedure. The provider will make a small cut (incision) over the biopsy site. He or she will insert the biopsy needle into your bone.

Do they numb you for a bone marrow biopsy? ›

You'll be awake during the procedure, but your provider will numb the biopsy site (local anesthesia) to keep you comfortable. Before the procedure, you'll change into a hospital gown. Your provider may give you a sedative to help you relax.

How deep does the needle go for bone marrow biopsy? ›

Alternatively (fig 2​), the bone marrow biopsy needle with its stilette in place is introduced just beyond the cortical bone. The stilette is then withdrawn and the needle advanced slowly by clockwise and counterclockwise rotary motion deep into the marrow cavity until an adequate depth (20–25 mm) is reached.

Is there an alternative to bone marrow biopsy? ›

Peripheral Blood Sample: An alternative to biopsy

An easier alternative to a biopsy would be a peripheral blood (PB) sample (i.e. the blood already circulating in the body, which is produced in the bone marrow).

Can I refuse a bone marrow biopsy? ›

You always have the right to refuse treatment.

Can you walk after a bone marrow biopsy? ›

Activity. Do light activities such as walking, unless you are told otherwise. Eat your normal diet, unless you are told otherwise. Most people are able to return to work the day after the procedure.

What is the premedication for bone marrow biopsy? ›

Premedication for biopsies

This may be with either an inhaler or an intravenous injection: Inhaled sedation, such as methoxyflurane or Penthrox. This is also known as the 'green whistle' and is an inhaled light acting pain relief. Intravenous sedation (midazolam) - supplies quicker and deeper sedation/drowsiness.

How uncomfortable is a bone marrow biopsy? ›

You may feel a pulling sensation as they do this. For a biopsy your doctor uses a slightly bigger needle to take the sample of bone marrow. They turn and push this needle to get the sample. This can be painful as the needle goes in but it doesn't last for long.

How long does a bone marrow biopsy take? ›

You may feel some pressure or pain at the site while the doctor removes the marrow and bone sliver. The pain usually lasts only a short time. To help yourself relax, take a deep breath. The test usually takes about 15 to 30 minutes.

Do you undress for a bone marrow biopsy? ›

Generally, a bone marrow biopsy follows this process: You will be asked to remove clothing and may be given a gown to wear. Your position may vary depending on the bone that is used. You may be asked to lie on your side or your stomach if the pelvis bone is used.

How do they numb you for bone marrow biopsy? ›

Depending on the biopsy site, you'll lie on your side or your belly. The most common bone marrow biopsy site is the back of your hip bone (posterior iliac crest). Your provider will clean your skin with an antiseptic and inject a numbing medication through your skin to the bone surface.

What helps bone marrow pain? ›

A doctor's diagnosis will determine the treatment, which may consist of:
  1. anti-inflammatories.
  2. antibiotics.
  3. painkillers (or analgesics)
  4. hormones.
  5. calcium and vitamin D supplements (for osteoporosis)
  6. anticonvulsants, where bone pain is nerve-related.
  7. corticosteroids.
  8. antidepressants.

How to relieve biopsy pain? ›

If you have pain after your biopsy, you can take acetaminophen (Tylenol®) as directed. If you have a history of liver disease, talk with your doctor before taking acetaminophen. Avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) for pain for 24 hours after your biopsy.

Is there an alternative to a bone marrow biopsy? ›

Peripheral Blood Sample: An alternative to biopsy

An easier alternative to a biopsy would be a peripheral blood (PB) sample (i.e. the blood already circulating in the body, which is produced in the bone marrow).

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